Analysis Note

ControlWestern Blot : Mouse brain lysate.

Application

This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).

General description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.

Immunogen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Saturated Ammonium Sulfate (SAS)

Quality

Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.

Specificity

The antibody reacts with the 29 kDa KLK3 antigen.

Other species have not been tested.

Storage and Stability

Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°

Target description

~31 kDa observed.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.